I’ve been pretty happy with mozy as an intermediate backup solution. It gives me automatic backups in the background to an offsite, secure location.
Basically I have mozy running a backup of my Outlook and Firefox profile — stuff that changes every day. Then on the weekends I back everything up to a USB hard drive at home.
You get 2gb for free, or an unlimited amount of storage if you sign up for a $6/mo plan.
Use this link to sign up for an account, and we both get a nice little 256mb bump in both our quotas: